Solvent Free Synthesis of tetra alkyl- phenyl-1H-pyrimido[4,5-e][1,3,4]Thiadiazine-3,7-diamines
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Abstract:
New 1,5-tetra alkyl methyl- phenyl-1H-pyrimido[4,5-e][1,3,4]thiadiazine-3,7-diamine were synthesized via the cyclocondensation of 2-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-2-methylhydrazine with phenylthioisothiocyanate and further replacement of chlorine atom on the seven number position of pyrimido[4, 5- e][1, 3, 4]thiadiazin by appropriate secondary amines in simple and efficient methods.
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Journal title
volume 7 issue 2
pages 25- 35
publication date 2017-11-01
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